Three‐tiered noninvasive diagnosis in 96% of patients with Duchenne muscular dystrophy (DMD)
- 27 January 2004
- journal article
- letter
- Published by Hindawi Limited in Human Mutation
- Vol. 23 (2), 203-204
- https://doi.org/10.1002/humu.10307
Abstract
A C 2-symmetrical aryl diphosphite derived from chiral binaphthol was prepared and its rhodium complex was used as catalysts in the asymmetric hydroformylation of olefins. High catalytic activity and good regioselectivity were observed. Up to 31.2% ee and 38.1% ee were achieved for the hydroformylation of 4-fluoro-styrene and vinyl acetate respectively. The influences of ligand-to-metal ratio, reaction temperature and the pressure of syn-gas on the enantioselectivity and regioselectivity were also studied.Department of Applied Biology and Chemical TechnologKeywords
This publication has 9 references indexed in Scilit:
- Genomic deletions of MSH2 and MLH1 in colorectal cancer families detected by a novel mutation detection approachBritish Journal of Cancer, 2002
- Comprehensive Detection of Genomic Duplications and Deletions in the DMD Gene, by Use of Multiplex Amplifiable Probe HybridizationAmerican Journal of Human Genetics, 2002
- Diagnosis of Duchenne dystrophy by enhanced detection of small mutationsNeurology, 2001
- Denaturing high-performance liquid chromatography: A reviewHuman Mutation, 2001
- Scanning by DOVAM-S Detects All Unique Sequence Changes in Blinded Analyses: Evidence that the Scanning Conditions Are GenericBioTechniques, 2000
- Detection of Virtually All Mutations-SSCP (DOVAM-S): A Rapid Method for Mutation Scanning with Virtually 100% SensitivityBioTechniques, 1999
- Denaturing high performance liquid chromatography (DHPLC) used in the detection of germline and somatic mutationsNucleic Acids Research, 1998
- Detection of 98% of DMD/BMD gene deletions by polymerase chain reactionHuman Genetics, 1990
- Deletion screening of the Duchenne muscular dystrophy locus via multiplex DNA amplificationNucleic Acids Research, 1988