Total synthesis of carboprostacyclin, a stable and biologically active analogue of prostacyclin (PGI2)
- 1 January 1978
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 23,p. 1067-1068
- https://doi.org/10.1039/c39780001067
Abstract
The total synthesis of the carbocyclic analogue (2) of prostacyclin (1) from cis-bicyclo[3.3.0]octane-3,7-dione (3) is described.This publication has 3 references indexed in Scilit:
- Synthesis and Biological Properties of Prostaglandin Endoperoxides, Thromboxanes and ProstacyclinsAngewandte Chemie International Edition in English, 1978
- The chemical structure of prostaglandin X (prostacyclin)Prostaglandins, 1976
- An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregationNature, 1976