EFFECTIVE RENAL BLOOD FLOW, GLOMERULAR FILTRATION RATE AND TUBULAR EXCRETORY MASS IN ARTERIAL HYPERTENSION

Abstract

In a previous paper¹ we reported the results of the determination of effective renal blood flow, glomerular filtration rate and tubular excretory mass by the diodrast and inulin clearance methods in 20 patients with arterial hypertension. It was concluded that arterial hypertension is associated with renal ischemia and that the reduction of blood supply to the kidney shows a definite correlation with the severity of the disease, as indicated by the changes, in the eyegrounds, the degree of thickening of the systemic arterioles, the renal function and the elevation of systolic and diastolic blood pressures. While this previous paper was in press, the results of similar studies were published by other investigators² who also concluded that the rate of renal blood flow is decreased in most cases of hypertension. The purpose of this paper is to report the results of the determination of effective renal blood flow, glomerular