Perfluorinated Organic Liquids and Emulsions as Biocompatible NMR Imaging Agents for 19F and Dissolved Oxygen
- 1 January 1984
- book chapter
- Published by Springer Nature
- Vol. 180, 835-845
- https://doi.org/10.1007/978-1-4684-4895-5_81
Abstract
Emulsions of fluorocarbons are finding considerable use in biology for intravascular oxygen transport. Their wide clinical application seems inminent (1). Because of their high content of the natural isotope of fluorine (19F), such emulsions will prove valuable in imaging the vascular and reticuloendothelial system by nuclear magnetic resonance (NMR). New, in addition, we have found that the paramagnetic effect of dissolved oxygen decreases the spin-lattice relaxation time (T1) of 19F in fluorocarbons and other highly fluorinated compounds, such as anesthetic agents, such that the imaging of oxygen in solution is possible.This publication has 6 references indexed in Scilit:
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- Survival of Mammals Breathing Organic Liquids Equilibrated with Oxygen at Atmospheric PressureScience, 1966