The effect of cerebellar stimulation on focal seizure activity and spasticity in monkeys

Abstract
In awake, unmedicated monkeys [Macaca arctoides] the effect of application of current to the cerebellar hemispheres on electrically induced focal motor seizures and surgically induced spasticity was determined. Application of current at various frequencies and pulse amplitudes did not significantly alter focal motor seizures but did significantly reduce spasticity. Analysis of evoked potential recordings carried out during various experimental procedures suggested that application of current to the cerebellar hemispheres may reduce cortical neuronal responsiveness.