Cell Population Kinetics: A Modified Interpretation of the Graph of Labeled Mitoses
- 23 May 1969
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 164 (3882), 952-954
- https://doi.org/10.1126/science.164.3882.952
Abstract
Graphs of labeled mitoses, derived from autoradiographs of cell populations with 3H-thymidine, show depressions in the curves at their midpoints. These depressions reflect interruption of DNA synthesis midway through S phase. Such interruptions revealed by the method of labeled mitoses should be considered when determining cell-cycle times.Keywords
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