Notch Activation Results in Phenotypic and Functional Changes Consistent With Endothelial-to-Mesenchymal Transformation
- 16 April 2004
- journal article
- research article
- Published by Wolters Kluwer Health in Circulation Research
- Vol. 94 (7), 910-917
- https://doi.org/10.1161/01.res.0000124300.76171.c9
Abstract
Various studies have identified a critical role for Notch signaling in cardiovascular development. In this and other systems, Notch receptors and ligands are expressed in regions that undergo epith...Keywords
This publication has 43 references indexed in Scilit:
- Effective contribution of transplanted vascular progenitor cells derived from embryonic stem cells to adult neovascularization in proper differentiation stageBlood, 2003
- Combinatorial effects ofFlk1andTal1on vascular and hematopoietic development in the mouseGenes & Development, 2003
- Analysis of Cardiovascular Phenotype and Genotype-Phenotype Correlation in Individuals With a JAG1 Mutation and/or Alagille SyndromeCirculation, 2002
- Members of the Jagged/Notch Gene Families Are Expressed in Injured Arteries and Regulate Cell Phenotype via Alterations in Cell Matrix and Cell-Cell InteractionThe American Journal of Pathology, 2001
- FoxH1(Fast) functions to specify the anterior primitive streak in the mouseGenes & Development, 2001
- Notch Signaling: Cell Fate Control and Signal Integration in DevelopmentScience, 1999
- Jagged1 mutations in patients ascertained with isolated congenital heart defectsAmerican Journal of Medical Genetics, 1999
- Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1Nature Genetics, 1997
- Endothelial Cell Death Induced by Tumor Necrosis Factor-α Is Inhibited by the Bcl-2 Family Member, A1Journal of Biological Chemistry, 1996
- An indirect immunofluorescence study of the distribution of fibronectin during the formation of the cushion tissue mesenchyme in the embryonic heartDevelopmental Biology, 1984