Synergy between Conserved ABC Signature Ser Residues in P-glycoprotein Catalysis
Open Access
- 1 February 2004
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 279 (7), 5363-5373
- https://doi.org/10.1074/jbc.m311964200
Abstract
No abstract availableKeywords
This publication has 45 references indexed in Scilit:
- P-glycoprotein Catalytic MechanismPublished by Elsevier ,2003
- Multidrug resistance in cancer: role of ATP–dependent transportersNature Reviews Cancer, 2002
- Conserved Walker A Ser Residues in the Catalytic Sites of P-glycoprotein Are Critical for Catalysis and Involved Primarily at the Transition State StepPublished by Elsevier ,2000
- Structural Biology of Rad50 ATPaseCell, 2000
- Both ATP Sites of Human P-Glycoprotein Are Essential but Not SymmetricBiochemistry, 1999
- ABC-ATPases, adaptable energy generators fuelling transmembrane movement of a variety of molecules in organisms from bacteria to humansJournal of Molecular Biology, 1999
- BIOCHEMICAL, CELLULAR, AND PHARMACOLOGICAL ASPECTS OF THE MULTIDRUG TRANSPORTERAnnual Review of Pharmacology and Toxicology, 1999
- Mutations in Either Nucleotide-Binding Site of P-glycoprotein (Mdr3) Prevent Vanadate Trapping of Nucleotide at Both SitesBiochemistry, 1998
- The catalytic cycle of P‐glycoproteinFEBS Letters, 1995
- Inorganic and organic phosphate measurements in the nanomolar rangeAnalytical Biochemistry, 1987