Adenylate cyclase and phosphodiesterase from brain tissue: Different stabilities during incubation of cerebral cortical slices

Abstract
Adenylate cyclase and phosphodiesterase were prepared from brain slices from guinea-pig. The specific acitivity of adenylate cyclase declined rapidly with increasing incubation time of tissue slices, while phosphodiesterase activity was almost uneffected by the incubation of brain slices.