The title of this paper, I take it, absolves me from any effort to enter at length into questions of the physics involved as well as into particular details as to dosage, which will therefore be handled lightly. I presume that my audience is largely one of general practitioners anxious to know only what dependence they are able to place on these novel remedies. The general term menstrual disorders covers a large field in gynecologic nosology, including as it does all conditions in which menstrual disturbances are a prominent symptom, even though they are secondary to some obvious gross lesion. The term encompasses also the disorders reflected from some focal infection and those due to some more or less unfathomable, hypothetic endocrine disturbance and, again, the group in which dysfunction is associated with some major psychic disorder, when the question is sure to arise whether the cessation of menstruation would