Production of Recombinant Mouse β-Interferon
- 1 August 1986
- journal article
- research article
- Published by Mary Ann Liebert Inc in Journal of Interferon Research
- Vol. 6 (4), 429-435
- https://doi.org/10.1089/jir.1986.6.429
Abstract
A plasmid was constructed to express a mouse β-interferon (IFN-β) in Escherichia coli under the control of the modified tryptophan (trp) promoter. E. coli carrying the plasmid were cultivated in a minijar fermentor and synthesized up to 2.7 × 106 IU/ml of antiviral activity. At the end of the cultivation the cells became elongated and curved.Keywords
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