Supramolecular DNA assembly
- 19 October 2011
- journal article
- review article
- Published by Royal Society of Chemistry (RSC) in Chemical Society Reviews
- Vol. 40 (12), 5647-5656
- https://doi.org/10.1039/c1cs15253j
Abstract
The powerful self-assembly features of DNA make it a unique template to finely organize and control matter on the nanometre scale. While DNA alone offers a high degree of fidelity in its self-assembly, a new area of research termed ‘supramolecular DNA assembly’ has recently emerged. This field combines DNA building blocks with synthetic organic, inorganic and polymeric structures. It thus brings together the toolbox of supramolecular chemistry with the predictable and programmable nature of DNA. The result of this molecular partnership is a variety of hybrid architectures, that expand DNA assembly beyond the boundaries of Watson–Crick base pairing into new structural and functional properties. In this tutorial review we outline this emerging field of study, and describe recent research aiming to synergistically combine the properties inherent to DNA with those of a number of supramolecular scaffolds. This ultimately creates structures with numerous potential applications in materials science, catalysis and medicine.This publication has 73 references indexed in Scilit:
- Designer DNA NanoarchitecturesBiochemistry, 2009
- Assembling Materials with DNA as the GuideScience, 2008
- Dynamic DNA Templates for Discrete Gold Nanoparticle Assemblies: Control of Geometry, Modularity, Write/Erase and Structural SwitchingJournal of the American Chemical Society, 2007
- From supramolecular chemistry towards constitutional dynamic chemistry and adaptive chemistryChemical Society Reviews, 2006
- Rotaxanes as ligands: from molecules to materialsChemical Society Reviews, 2006
- Reversible guest exchange mechanisms in supramolecular host–guest assembliesChemical Society Reviews, 2006
- Sequential Self‐Assembly of a DNA Hexagon as a Template for the Organization of Gold NanoparticlesAngewandte Chemie International Edition, 2006
- DNA in a material worldNature, 2003
- Self-Assembly of Trisoligonucleotidyls: The Case for Nano-Acetylene and Nano-CyclobutadieneAngewandte Chemie International Edition, 1999
- Assembly of Novel DNA Cycles with Rigid Tetrahedral LinkersAngewandte Chemie International Edition in English, 1997