BASIC PERFORMANCE TESTS ON THE CERVIFIP LINEAR-ARRAY PRESCREENER

Abstract

CERVIFIP is a computer image-analysis prescreener for [human] cervical cytology specimens. It is based on the Fast Interval Processor, a high-speed image analyzer, which uses a linear, charge-coupled, photodiode array scanner and a hardwired image data preprocessor unit for image data reduction prior to input to a computer. The software for CERVIFIP carries out real-time measurements and hierarchic classification of cells based on nuclear DNA content, morphologic and densitometric features for artifact rejection and operator review of cells suspected of being atypical. Preliminary tests have shown that the system is capable of accurate measurement of integrated optical density and positional information on cells at rates in excess of 30,000 cells/min.