Alterations in Vitamin A Metabolism During Zinc Deficiency and Food and Growth Restriction
- 1 April 1976
- journal article
- research article
- Published by Elsevier in Journal of Nutrition
- Vol. 106 (4), 569-574
- https://doi.org/10.1093/jn/106.4.569
Abstract
The purpose of these experiments was to further elucidate the effect of the trace element, zinc, on vitamin A metabolism. Three experiments were conducted at two different locations using different sources of animals. A total of 95 rats were used; 71 specific pathogen free and 24 germfree. The results indicate that plasma vitamin A is depressed in zinc deficient animals or animals severely restricted in food and growth. Liver stores of vitamin A were adequate in both groups. Thus, the normal mechanism for maintaining plasma vitamin A appears to be altered by either zinc deficiency and/or severe food and growth restriction.Keywords
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