The Effects of Vasodilation with Prostacyclin on Oxygen Delivery and Uptake in Critically Ill Patients
- 13 August 1987
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 317 (7), 397-403
- https://doi.org/10.1056/nejm198708133170701
Abstract
We hypothesized that inadequate oxygenation of peripheral tissues may be unrecognized in critically ill patients and may worsen their prognosis. To test this hypothesis, we measured oxygen delivery to tissues, oxygen uptake, and the extraction ratio (uptake/delivery) before and during a 30-minute infusion of a vasodilator, prostacyclin (5 ng per kilogram of body weight per minute), in 27 critically ill patients with acute respiratory failure.Keywords
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