Abstract
Four instances of bacterial actinophytosis (true human botryomycosis) in soft tissue are reported. In one case Actinobacillus lignieresi was responsible and in the other 3 it was believed that staphylococci were the causative agents. Bacteria may give rise in tissue to granules indistinguishable from actinomycotic granules in routine stained sections. The use of bacterial staining methods may establish the histologic diagnosis.

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