ADH and ALDH genotype profiles in Caucasians with alcohol‐related problems and controls
- 1 March 1993
- Vol. 88 (3), 383-388
- https://doi.org/10.1111/j.1360-0443.1993.tb00825.x
Abstract
Eighty-two Caucasian patients receiving treatment for alcohol-related problems and eighty four controls were DNA typed for variants in the alcohol dehydrogenase (ADH2 and ADH3) and mitochondrial aldehyde dehydrogenase (ALDHJ gene loci. No association was observed between individual, or combined gene frequencies and the presence of alcohol-related problems.Keywords
This publication has 19 references indexed in Scilit:
- Allelic Association of Human Dopamine D2 Receptor Gene in AlcoholismJAMA, 1990
- Allelic association of human dopamine D2 receptor gene in alcoholismJAMA, 1990
- Genotyping of human class I alcohol dehydrogenase Analysis of enzymatically amplified DNA with allele‐specific oligonucleotidesFEBS Letters, 1988
- The gamma1 and gamma2 subunits of human liver alcohol dehydrogenase. cDNA structures, two amino acid replacements, and compatibility with changes in the enzymatic propertiesEuropean Journal of Biochemistry, 1986
- Report of the committee on the genetic constitution of chromosomes 7, 8 and 9Cytogenetic and Genome Research, 1985
- Alcohol sensitivity related to polymorphism of alcohol-metabolizing enzymes in JapanesePharmacology Biochemistry and Behavior, 1983
- Human liver alcohol dehydrogenase: ADHIndianapolis results from genetic polymorphism at the ADH 2 gene locusBiochemical Genetics, 1983
- Genetic Determinants of Alcohol and Aldehyde Dehydrogenases and Alcohol MetabolismSeminars in Liver Disease, 1981
- Alcohol dehydrogenase isozymes in adult human stomach and liver: evidence for activity of the ADH3 locusAnnals of Human Genetics, 1972
- Developmental changes and polymorphism in human alcohol dehydrogenaseAnnals of Human Genetics, 1971