The Effect of Surgical Operations on the Bromsulfalein-Retention Test

Abstract

THERE are several reports in the literature dealing with the effect of surgical operations on liver function. The available material was recently reviewed.^{1 , 2} Most workers report changes in a high proportion of patients after surgery under general or spinal anesthesia. The hippuric acid test was used in several cases but has been criticized on theoretical grounds. The principal objection is that it depends on the integrity of kidney function, which may be impaired immediately after a surgical operation. Other authors have reported results obtained with the bromsulfalein-retention test using an injection of 2 mg. of the dye per kilogram of . . .