A novel form of dependency of hepatic extraction ratio of opioids in vivo upon the portal vein concentration of drug: Comparison of morphine, diamorphine, fentanyl, methadone and buprenorphine in the chronically cannulated cow
- 1 May 1984
- journal article
- research article
- Published by Elsevier in Life Sciences
- Vol. 34 (21), 2047-2056
- https://doi.org/10.1016/0024-3205(84)90369-2
Abstract
No abstract availableThis publication has 22 references indexed in Scilit:
- ACUTE I.V. METHADONE KINETICS IN MAN: RELATIONSHIP TO CHRONIC STUDIESBritish Journal of Anaesthesia, 1982
- The radioimmunoassay of buprenorphineEuropean Journal of Clinical Pharmacology, 1980
- A sensitive radioimmunoassay for fentanylEuropean Journal of Clinical Pharmacology, 1977
- Perfusion-limited effects of plasma drug binding on hepatic drug extractionLife Sciences, 1976
- Some observations on metabolite production and utilizationin vivoby the gut and liver of adult dairy cowsThe Journal of Agricultural Science, 1975
- Clearance concepts in pharmacokineticsJournal of Pharmacokinetics and Biopharmaceutics, 1973
- Canimlation of an Hepatic Vein, the Portal Vein and a Mesenteric Vein in the Cow, and its Use in the Measurement of Blood Flow RatesResearch in Veterinary Science, 1973
- Application of clearance concepts to some literature data on drug metabolism in the isolated perfused liver preparation and in vivoEuropean Journal of Pharmacology, 1972
- Theory of the Measurement of the Dispersion of an Indicator in Indicator-Dilution StudiesCirculation Research, 1962
- THEORY OF THE USE OF ARTERIOVENOUS CONCENTRATION DIFFERENCES FOR MEASURING METABOLISM IN STEADY AND NON-STEADY STATES*Journal of Clinical Investigation, 1961