Determination of DNA sequence changes induced by ethyl methanesulfonate in human cells, using a shuttle vector system.
Open Access
- 1 May 1986
- journal article
- research article
- Published by Taylor & Francis in Molecular and Cellular Biology
- Vol. 6 (5), 1838-1842
- https://doi.org/10.1128/mcb.6.5.1838
Abstract
The DNA sequence changes for 54 mutations induced in human cells by the alkylating agent ethyl methanesulfonate are reported. The mutations were obtained by using a shuttle vector system with the bacterial lacI gene as the target. Of the 54 mutations obtained, 53 were G:C to A:T transitions.This publication has 25 references indexed in Scilit:
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