THE USE OF XENOPUS LAEVIS, BUFO BUFO, AND RANA ESCULENTA AS TEST ANIMALS FOR GONADOTROPHIC HORMONES

Abstract

The first article in this series (Thorborg, 1950 a) dealt with the anatomy, physiology and biology of Xenopus laevis, Bufo bufo and Rana esculenta. In the second article (Thorborg, 1950 b) the literature on the qualitative and quantitative response of batrachia to gonadotrophic hormones was reviewed. Although several authors have determined the sensitivity of their test animals to chorionic gonadotrophin these sensitivity tests do not appear to have been performed throughout the whole year. The question whether seasonal variations in the sensitivity of the animals exist has not been fully answered. The purpose of the present investigations has been to determine the sensitivity of the test animals to chorionic gonadotrophin under laboratory conditions with special reference to seasonal variations. *) The work has been aided by grants from the »Løvens kemiske Fabriks Legat« and the P. Carl Petersen Foundation. As the most reliably results were obtained with the male Bufo