Secondary Syphilis

Abstract

We report herein four cases of nodular syphilis, a rare form of secondary syphilis that closely simulates lymphoma and granulomatous disease processes of variable origins. We discuss the clinical presentations, serologic and histologic features, treatment, and course of these patients and review the manifestations of secondary syphilis. We conclude that secondary syphilis is still the great imitator. (JAMA1983;249:3069-3070)