Histological Changes in the Brain After Uncomplicated Electro-Convulsant Treatment

Abstract

There has been much discussion about the possible occurrence of reversible and irreversible histological changes in the brain following the convulsive treatment of mental disorder. Most investigations have been carried out either on experimental animals—with results not easily comparable to man—or in deceased patients in whom the picture is usually obscured by the presence of complications. The various causes of death following convulsive treatment have recently been reviewed by Maclay (1953).