Abstract
1. The vagus nerve of the gopher-snake, Drymarchon corais couperi (Holbrook), discharges carbon dioxide at an average rate of 0.00234 mgm. of gas per gram of nerve per minute. The extremes were 0.0032 mgm. and 0.0017 mgm. 2. These rates were maintained as well when the nerve was separated from its central and its peripheral connections as when these connections were intact showing that the resting metabolism of nerve is a local operation and is not immediately dependent upon distant connections. 3. These observations also point to the conclusion that the passage of normal impulses over a nerve call for an increase of activity that is unobservable by the method employed and that must be small in amount compared with that produced by artificial stimulation.

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