A Polygalacturonate Lyase Produced by Lachnospira multiparus Isolated from the Bovine Rumen

Abstract
A poly(1,4-.alpha.-D-galacturonide) lyase (EC 4.2.2.2) from the culture fluid of L. multiparus was purified about 20-fold. The optimum pH and temperature for enzyme activity were 8.0 and 40.degree. C. The enzyme required Ca2+ and was inhibited by EDTA; it preferred polygalacturonate as substrate, cleaving 1,4-.alpha.-glycosidic linkages randomly to form unsaturated galacturonates, mainly the unsaturated digalacturonate. Some properties of the crude and purified enzyme preparations are described. An exopolygalacturonase is also produced by this organism.
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