Proton correlation nuclear magnetic resonance study of anaerobic metabolism of Escherichia coli

Abstract

Proton correlation NMR was used to investigate anaerobic metabolism of glucose in E. coli cells. The time course of the concentrations of 6 metabolites (ethanol, lactate, acetate, pyruvate, succinate and formate) was followed at the very early stage of fermentation, and used to discuss dynamical aspects of the mixed-acid fermentation of glucose by E. coli.