Comparative studies of five heat-labile toxic products of Escherichia coli
- 1 December 1978
- journal article
- research article
- Published by American Society for Microbiology in Infection and Immunity
- Vol. 22 (3), 644-648
- https://doi.org/10.1128/iai.22.3.644-648.1978
Abstract
Five heat-labile, partially purified toxic products of Escherichia coli were distinguished by isoelectric focusing, molecular weight, and neutralization with homologous and heterologous antisera. Only two affected the morphology of Y-1 cells, induced fluid accumulation in rabbit ileal loops, and stimulated production of cyclic AMP in Vero cells; these two did not cross-neutralize and only one showed cross-neutralization with cholera antitoxin. The remaining three products were cytotoxic for Vero cells.This publication has 11 references indexed in Scilit:
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