Hydroxylation of aromatic compounds by reduced nicotinamide-adenine dinucleotide and phenazine methosulphate requires hydrogen peroxide and hydroxyl radicals, but not superoxide
- 1 October 1977
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 167 (1), 317-320
- https://doi.org/10.1042/bj1670317
Abstract
A mixture of NADH and phenazine methosulfate [which may represent a model system for oxygenase enzymes] hydroxylates aromatic compounds at acidic pH values. Hydroxylation is inhibited by catalase and by scavengers of the hydroxyl radical .**GRAPHIC**. but not by superoxide dismutase [EC 1.15.1.1]. Apparently, neither .**GRAPHIC**. is sufficiently reactive to hydroxylate aromatic rings.This publication has 13 references indexed in Scilit:
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