Phosphorylation of Ser307 in Insulin Receptor Substrate-1 Blocks Interactions with the Insulin Receptor and Inhibits Insulin Action
Top Cited Papers
Open Access
- 1 January 2002
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 277 (2), 1531-1537
- https://doi.org/10.1074/jbc.m101521200
Abstract
No abstract availableKeywords
This publication has 54 references indexed in Scilit:
- Obesity and insulin resistanceJournal of Clinical Investigation, 2000
- Molecular Cloning of Rat SH2-Containing Inositol Phosphatase 2 (SHIP2) and Its Role in the Regulation of Insulin SignalingBiochemical and Biophysical Research Communications, 1999
- Inhibition of IRS-1 Phosphorylation and the Alterations of GLUT4 in Isolated Adipocytes from Cachectic Tumor-Bearing RatsBiochemical and Biophysical Research Communications, 1999
- Interaction of Insulin Receptor Substrate-1 (IRS-1) with Phosphatidylinositol 3-Kinase: Effect of Substitution of Serine for Alanine in Potential IRS-1 Serine Phosphorylation SitesEndocrinology, 1998
- Protein Kinase C Modulates the Insulin-Stimulated Increase in Akt1 and Akt3 Activity in 3T3-L1 AdipocytesBiochemical and Biophysical Research Communications, 1998
- The Pleckstrin Homology Domain Is the Principle Link between the Insulin Receptor and IRS-1Journal of Biological Chemistry, 1996
- PTB Domains of IRS-1 and Shc Have Distinct but Overlapping Binding SpecificitiesPublished by Elsevier ,1995
- Tumor Necrosis Factor α-induced Phosphorylation of Insulin Receptor Substrate-1 (IRS-1)Journal of Biological Chemistry, 1995
- JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domainCell, 1994
- Activation of protein kinase C alpha inhibits insulin-stimulated tyrosine phosphorylation of insulin receptor substrate-1Molecular Endocrinology, 1994