Risk factors for corneal endothelial injury during phacoemulsification
- 1 October 1996
- journal article
- Published by Wolters Kluwer Health in Journal of Cataract & Refractive Surgery
- Vol. 22 (8), 1079-1084
- https://doi.org/10.1016/s0886-3350(96)80121-0
Abstract
Ge of corneal endothelial cell loss at 3 months after surgery was quantitated using specular microscopy. The firmness of the nucleus was graded by Emery’s classification prior to surgery. We selected nine variables that could be associated with endothelial injury. The univariate associations between the endothelial cell loss and these variables were evaluated using simple correlation coefficients. A multiple linear regression analysis was performed to identify independent predictors of endothelial cell loss. Results: In the simple regression analysis, older age, small pupil diameter, high nucleus grade, large nucleus, greater infusion volume, type of IOL implanted, and a greater amount of total emitted ultrasound energy were univariately associated with endothelial cell loss. In the multiple linear regression analysis, the best final model (R2 = 0.42) identified high nucleus grade, greater infusion volume, type of IOL implanted, and large nucleus as independent predictors of endothelial cell loss. Conclusion: Both univariate and multivariate analyses identified the firmness of the nucleus as the most significant risk factor for endothelial cell loss. Therefore, mechanical contact with nuclear fragments is considered the principal cause of endothelial injury. *Reprint requests to Ken Hayashi, MD, Hayashi Eye Hospital, 4-713 Hakataekimae, Hakata-ku, Fukuoka 812, Japan. None of the authors has a proprietary interest in the materials described Noriya Taki, PhD, helped with the statistical analysis. © Williams & Wilkins 1996. All Rights Reserved....Keywords
This publication has 15 references indexed in Scilit:
- Corneal endothelial cell loss in phacoemulsification surgery with silicone intraocular lens implantationJournal of Cataract & Refractive Surgery, 1996
- A Comparison of Corneal Endothelial Changes After Use of Healon or Viscoat During PhacoemulsificationAmerican Journal of Ophthalmology, 1993
- Endothelial Protection and Viscoelastic Retention During Phacoemulsification and Intraocular Lens ImplantationArchives of Ophthalmology (1950), 1991
- Air bubble endothelial damage during phacoemulsification in human eye bank eyes: The protective effects of Healon and ViscoatJournal of Cataract & Refractive Surgery, 1990
- Endothelial Trauma and Cell Loss From Intraocular Lens InsertionArchives of Ophthalmology (1950), 1978
- The Effect of Phacoemulsification on Corneal Endothelial Cell DensityArchives of Ophthalmology (1950), 1978
- Effects of ultrasound on the corneal endothelium: I. The acute lesion.British Journal of Ophthalmology, 1978
- Corneal Endothelial Damage Associated by PhacoemulsificationAmerican Journal of Ophthalmology, 1976
- Endothelial Damage Associated with Intraocular LensesAmerican Journal of Ophthalmology, 1976
- Intraocular Irrigating SolutionsArchives of Ophthalmology (1950), 1975