Neurological sequelae in children surviving mechanical ventilation in the neonatal period.

Abstract

The incidence of mental defect, visual and hearing disability, major neurological handicap and such minor neurological handicap as could be detected on examination at 2-9 yr without formal intelligence testing, was presented among survivors of neonatal mechanical ventilation. Of 367 children, 77 (21%) survived, over 3/4 being born elsewhere. Three died before the age of 6 mo., 2 suddenly and unexpectedly at home, the 3rd accidentally. One child was lost to follow up. Of the remaining 73 children, 11 (15%) had neurological sequelae as defined. In 2/3 this was moderate to severe. Spastic diplegia may no longer be the commonest form of cerebral palsy among those of low birthweight, particularly those surviving severe neonatal illness.