Tubulin requires tau for growth onto microtubule initiating sites.
- 1 November 1976
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 73 (11), 4070-4074
- https://doi.org/10.1073/pnas.73.11.4070
Abstract
Tubulin [porcine brain] purified by phosphocellulose chromatography and free of accessory proteins will not form microtubules in the absence or presence of microtubule initiating sites (flagellar microtubules). The capacity for growth onto pre-existing seeds can be restored by the addition of small quantities of partially purified tau[.female.] protein. Larger quantities restore the capacity for spontaneous assembly. Tubulin probably requires .female. for both initiation and growth of microtubules may be incorporated into the microtubule throughout its length.This publication has 26 references indexed in Scilit:
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