Translocation of hepatic cytosol androgen receptor to the nucleus in vivo in male rats

Abstract
Testosterone, which was injected s.c. into adult male rats castrated 15 h prior to the injection, decreased the number of androgen-specific binding sites in the cytosol at 30 min. Coincidentally, a substantial increase was observed in the nucleus. The decreased number of the sites in the cytosol was restored to the initial level at 60 min; on the contrary, a decrease was observed in the nucleus.