Hyperserotonemia and Early Infantile Autism
- 15 July 1982
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 307 (3), 181-183
- https://doi.org/10.1056/nejm198207153070310
Abstract
IN this issue of the Journal, Geller and his colleagues show that the administration of fenfluramine to three autistic children lowered platelet serotonin and was followed by improvement in clinical symptoms, social behavior, and IQ.1 This finding may have important implications in the treatment of infantile autism and may cast much-needed new light on this bewildering disorder.The past 30 years have seen a marked shift in our perspective on infantile autism. In the 1950s autism was pronounced a psychologic disorder, the "rage reaction" of the child against the mother's unconscious wish that he or she did not exist. . . .Keywords
This publication has 4 references indexed in Scilit:
- Preliminary Observations on the Effect of Fenfluramine on Blood Serotonin and Symptoms in Three Autistic BoysNew England Journal of Medicine, 1982
- Drs. Ornitz and Ritvo ReplyAmerican Journal of Psychiatry, 1976
- Causes of infantile autism: Some considerations from recent researchJournal of Autism and Developmental Disorders, 1971
- Studies on 5-hydroxyindole metabolism in autistic and other mentally retarded childrenThe Journal of Pediatrics, 1961