Low molecular weight peptides controlling transcription are present in the calf thymus chromatin structure
- 1 December 1977
- journal article
- research article
- Published by Springer Nature in Molecular Biology Reports
- Vol. 3 (6), 429-436
- https://doi.org/10.1007/bf00808384
Abstract
A calf thymus peptide fraction controlling DNA and chromatin template has been purified by DNA-cellulose and Dowex 50 WX2 chromatography and its amino acid composition determined. The active peptide fraction can be extracted in high pH buffer from calf thymus native chromatin previously deproteinized by chloroform-isoamylalcohol and phenol. These data demonstrate that the thymic peptide(s) is (are) a chromatin protein constituent strongly linked to DNA. The specificity in association of the peptide(s) to DNA has also been considered.This publication has 11 references indexed in Scilit:
- DNA-protein interactionsNature, 1977
- Stabilization of double-stranded DNA molecule by nonhistone peptidic effector from calf thymusMolecular Biology Reports, 1976
- Restriction of template capacity of rat liver chromatin by a non-histone peptide from calf thymusNature, 1976
- Evidence for the presence in calf thymus of a peptidic factor controlling DNA transcription in vitroBiochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1975
- Tissue-Specific Transcription of the Globin Gene in Isolated ChromatinProceedings of the National Academy of Sciences, 1973
- Purification of a DNA polymerase from calf thymus nucleiBiochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1972
- A Deoxyribonucleic Acid Polymerase from Micrococcus luteus (Micrococcus lysodeikticus) Isolated on Deoxyribonucleic Acid-CelluloseJournal of Biological Chemistry, 1968
- The preparation of deoxyribonucleic acids by the p-aminosalicylate-phenol methodBiochimica et Biophysica Acta, 1959
- PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENTJournal of Biological Chemistry, 1951