Electroencephalogram Effect Measures and Relationships Between Pharmacokinetics and Pharmacodynamics of Centrally Acting Drugs
- 1 September 1992
- journal article
- review article
- Published by Springer Nature in Clinical Pharmacokinetics
- Vol. 23 (3), 191-215
- https://doi.org/10.2165/00003088-199223030-00003
Abstract
Electroencephalogram (EEG) effect parameters may be useful in pharmacokinetic-pharmacodynamic modelling studies of drug effects on the central nervous system (CNS). Effect parameters derived from a...Keywords
This publication has 99 references indexed in Scilit:
- Estimation of amobarbital plasma-effect site equilibration kinetics. Relevance of polyexponential conductance functionsJournal of Pharmacokinetics and Biopharmaceutics, 1991
- Pharmacokinetic-Pharmacodynamic Modelling of the Interaction between Flumazenil and Midazolam in Volunteers by Aperiodic EEG AnalysisClinical Pharmacokinetics, 1991
- Pharmacodynamic characterization of the electroencephalographic effects of thiopental in ratsJournal of Pharmacokinetics and Biopharmaceutics, 1991
- Pharmacokinetic-pharmacodynamic modeling of the central nervous system effects of heptabarbital using aperiodic EEG analysisJournal of Pharmacokinetics and Biopharmaceutics, 1990
- Quantification of the EEG Effect of Midazolam by Aperiodic Analysis in VolunteersClinical Pharmacokinetics, 1990
- Pharmacodynamic modeling of the EEG effects of ketamine and its enantiomers in manJournal of Pharmacokinetics and Biopharmaceutics, 1987
- Intravenous Anaesthetic AgentsClinical Pharmacokinetics, 1987
- Pharmacodynamic Interaction Between Midazolam and a Specific Benzodiazepine Antagonist in HumansThe Journal of Clinical Pharmacology, 1985
- Several new benzodiazepines selectively interact with a benzodiazepine receptor subtypeNeuroscience Letters, 1983
- Drug Effects on the EEG of Various Species of Laboratory AnimalsNeuropsychobiology, 1983