The Management of Advanced Testicular Teratoma

Abstract
Summary— Of 320 patients with metastatic malignant non‐seminomatous germ cell tumours of the testis (NSGCT) treated with chemotherapy, 266 (83%) are alive and well after a median follow‐up of 39 months. Deaths from treatment‐related causes occurred in 9 patients and were related to intensity of chemotherapy. Relapse after chemotherapy was rare except in presentations with large tumour volume and high serum marker concentrations and a strategy has been developed of risk‐related choice of chemotherapy in order to reduce treatment toxicity in good prognosis sub‐groups of patients.