Emergence of NDM-1-Producing Enterobacteriaceae in Belgium

Abstract
Five multidrug-resistant nonclonally related Enterobacteriaceae isolates were recovered in Belgium in 2010 from three patients who had been hospitalized in Pakistan, Montenegro, and Serbia/Kosovo. New Delhi metallo-β-lactamase (NDM-1) was detected in each of the isolates in addition to several extended-spectrum β-lactamases (CTX-M-15, SHV-12), plasmidic cephalosporinases (CMY-16, CMY-58), rRNA methylases (ArmA, RmtB), and Qnr genes ( qnrA6 , qnrB1 , qnrB2 ). One patient died from uncontrolled sepsis, while the two others recovered. No secondary cases occurred in any of the hospitals.

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