Studies in Testicular Function. I. Quantitative Effects of FSH, LH, Testosterone and Dihydro-testosterone on Restoration and Maintenance of Spermatogenesis in the Hypophysectomized Rat

Abstract

Male Wistar rats were hypophysectomized and the effects on spermatogenesis were quantified by stereological techniques. Restoration of normal spermatogenesis was attempted 32 days after hypo-physectomy by treatment with FSH (designated F), LH (L) or testosterone (T) singly or in combina-tion for a further 32 days. In another experiment, maintenance of spermatogenesis was attempted using FSH (F), testosterone (T) or dihydrotestoterone (D). Treatment began two days after hypo-physectomy and was continued for a further 32 days.