Abstract
To the Editor: The editorial by Engel and Salzman, "A Double Standard for Psychosomatic Papers?" (N Engl J Med 288:44–46, 1973), observed that our paper, "A Controlled Therapeutic Study of the Irritable-Bowel Syndrome: Effect of diphenylhydantoin," was one "of two psychosomatic papers." The article is, in fact, a double-blind crossover evaluation of the drug diphenylhydantoin in patients suffering from the irritable-bowel syndrome. Our use of the Willoughby schedule was as a preliminary screening device in the event that differences were found in patients receiving diphenylhydantoin and placebo. It was then our plan to carry out further clinical and psychologic tests . . .