Engines, Accelerators, and Brakes on Functional Spinal Cord Repaira
- 1 November 1998
- journal article
- Published by Wiley in Annals of the New York Academy of Sciences
- Vol. 860 (1), 412-424
- https://doi.org/10.1111/j.1749-6632.1998.tb09065.x
Abstract
It is proposed that four essential goals should be met for functional repair after traumatic injury of the adult spinal cord. These include protecting neural tissue after injury and limiting secondary cell damage; replacing lost tissue with transplanted cell "bridges"; blocking the expression of intrinsic factors within the adult CNS that inhibit neural repair; and providing appropriate sensorimotor activity to enhance plasticity within surviving circuits, as well as consolidate any anatomical repair/regeneration. Included is a brief discussion on the approaches and limitations in the evaluation of functional spinal cord repair.This publication has 53 references indexed in Scilit:
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