Antineoplastic Agents, 162. Zephyranthes candida

Abstract
The Chinese medicinal plant Zephyranthes candida was found to contain a cytostatic constituent. Separation of a n-BuOH extract directed by results of a bioassay employing the P-388 lymphocytic leukemia led to trans-dihydronarciclasine [2] as the principal cytostatic agent with ED50 3.2 .times. 10-3 .mu.g/ml.

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