Impaired Pancreatic Polypeptide Secretion in Chronic Pancreatitis*
- 1 September 1978
- journal article
- research article
- Published by The Endocrine Society in Journal of Clinical Endocrinology & Metabolism
- Vol. 47 (3), 556-559
- https://doi.org/10.1210/jcem-47-3-556
Abstract
In patients with chronic pancreatitis, the plasma pancreatic polypeptide (PP) response to insulininduced hypoglycemia is impaired, although basal levels are within the normal range. Somatostatin lowers the PP response in normal people and in patients with chronic pancreatitis. The PP response may be a useful index of pancreatic function.Keywords
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- Does somatostatin inhibition of insulin secretion involve two mechanisms of action?Proceedings of the National Academy of Sciences, 1976