Identification of a C -Glucuronide of Δ 6 -Tetrahydrocannabinol as a Mouse Liver Conjugate in vivo
- 23 June 1978
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 200 (4348), 1391-1392
- https://doi.org/10.1126/science.200.4348.1391
Abstract
Δ6-Tetrahydrocannabinol-C-4'- glucuronide was found in the livers of mice that had been administered Δ6-tetrahydrocannabinol. Thus, C-glucuronidation of a compound that contains a free hydroxyl group has been demonstrated in vivo.This publication has 6 references indexed in Scilit:
- Synthesis and enzymic formation of a C-glucuronide of .DELTA.6-tetrahydrocannabinolJournal of the American Chemical Society, 1977
- IDENTIFICATION OF GLUCURONIDES AS INVIVO LIVER CONJUGATES OF 7 CANNABINOIDS AND SOME OF THEIR HYDROXY AND ACID METABOLITES1977
- Recent advances in the chemistry and biochemistry of cannabisChemical Reviews, 1976
- C‐Glucuronides, a Novel Type of Drug MetabolitesHelvetica Chimica Acta, 1975
- Biliary excretion of Δ1-tetrahydrocannabinol and its metabolites in the ratBiochemical Pharmacology, 1974
- Isolation and structure of .DELTA.+- tetrahydrocannabinol and other neutral cannabinoids from hashishJournal of the American Chemical Society, 1971