The Gamma Globulins

Abstract

THE work of Cohn and his colleagues in the 1940's made feasible large-scale fractionation of serum proteins by precipitation with ethanol under carefully controlled conditions in the cold. Cohn Fraction II contains principally the serum γG globulin and only trace amounts of γA and γM globulins. It is commercially available as a 16.5 per cent slightly opalescent, colorless solution when prepared from ordinary plasma and with a brownish color when prepared from placental blood. The solution contains glycine and merthiolate as stabilizer and preservative. Gamma globulin is also distributed by the American Red Cross and is available through many state . . .