Treatment of Advanced Breast Cancer with Chemotherapeutics and Inhibition of Coagulation and Fibrinolysis

Abstract
A case of advanced breast cancer with cerebral metastases and pleurisy is reported in which irradiation and cytostatics failed to retard progressive growth and spread of the tumor. Adjuvant therapy with heparin combined with the fibrinolytic inhibitor tranexamic acid was followed by regression of the cerebral metastases as well as the pleurisy. When last seen 1 yr later, the patient was free from symptoms.