THE INFLUENCE OF ESTRIOL, ESTRADIOL AND PROGESTERONE ON THE SECRETION OF GONADOTROPIC HORMONES IN PARABIOTIC RATS1

Abstract

Data are presented on the amts. of hormone required to prevent hypersecretion of gonadotrophic hormone after castration of a [male] in [female]-[female] pairs and of the [male] in [female]-[male] pairs. The order of effectiveness (estradiol> estrone > estriol) was the same as that in producing vaginal cornification. The [male] pituitary secreted very little, if any, more gonadotrophic hormone in 10 days after castration than does the $ pituitary.