Loffler's Eosinophilic Endocarditis with Balint's Syndrome (Optic Ataxia and Paralysis of Visual Fixation)

Abstract

Four patients who presented with, neurological symptoms, eosinophilia, and latent cardiac lesions are described, with two autopsy studies. They were believed to have Loffler's eosinophilic endocarditis, or disseminated eosinophilic collagen disease. Problems concerning the nature and nomenclature of the disorder, its relationship to Loffler's pneumonia and various cardiomyopathies, and its aetiology are discussed. The frequency with which the disease produces bilateral hemisphere damage, and in particular a perplexing form of ataxia and impaired vision due to parieto-occipital lesions (Balint's syndrome) is indicated.