The addition of permethrin as a scabicide with low toxicity adds significantly to our therapeutic options for typical and special forms of scabies. Detailed specific management suggestions, as well as a scabies instruction sheet, are included. The management of crusted (Norwegian) scabies and scabies in human immunodeficiency virus-acquired immune deficiency syndrome (HIV/AIDS) is more difficult and may require, particularly in those intensely immunosuppressed, repeated treatment with scabicides and sometimes sequential use of several agents. Tolerance (resistance) to lindane was suggested in Central America but also in South America, Haiti, Egypt, and in clusters in the United States.