Oxidation of aliphatic hydroxylamines in aqueous solutions
- 1 September 1977
- journal article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 29 (1), 15-21
- https://doi.org/10.1111/j.2042-7158.1977.tb11230.x
Abstract
The effects of pH, buffer constituents, duration of storage, presence of air, heavy metal ions, extracting solvents and various additives and cofactors on the aerial oxidation of some aliphatic primary and secondary hydroxylamines were investigated. Copper ions were particularly effective catalysts of the oxidation reaction. Conditions to minimize this transformation are described.Keywords
This publication has 14 references indexed in Scilit:
- N-Hydroxylation of 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane by rabbit liver microsomesJournal of Medicinal Chemistry, 1975
- Synthetic routes to optical isomers of primary and secondary hydroxylamines of 1-arylisopropylaminesTetrahedron, 1975
- The mechanism of metabolic N-oxidation of phentermine and chlorphentermine to their hydroxylamino- and nitroso-compoundsJournal of Pharmacy and Pharmacology, 1974
- N-Oxidation of primary and secondary amines to give hydroxylamines—a general metabolic routeJournal of Pharmacy and Pharmacology, 1972
- Metabolic Oxidation of Aliphatic Basic Nitrogen Atoms and their α-Carbon AtomsXenobiotica, 1971
- Chemistry of singlet oxygen. VII. Quenching by .beta.-caroteneJournal of the American Chemical Society, 1968
- Determination and identification of amphetamine in urineJournal of Pharmacy and Pharmacology, 1965
- NitronesChemical Reviews, 1964
- The Interaction of Chelating Agents with BacteriaJournal of Pharmacy and Pharmacology, 1958
- 229. Aliphatic hydroxylamines. Part II. AutoxidationJournal of the Chemical Society, 1956